Synonyms[]
- CD246
Antibodies[]
Technical Info[]
Staining Pattern[]
Expression in Normal Tissues[]
Expression in Neoplastic Entities[]
Benign[]
Tumor name | % Positive Staining | Number of Cases | ||||
Inflammatory myofibroblastic tumor (IMT) | 60%[1] | 73[1] | - | |||
Intermediate/Uncertain Malignant Potential[]
Tumor name | % Positive Staining | Number of Cases |
Malignant[]
Tumor name | % Positive Staining | Number of Cases |
Anaplastic large cell lymphoma (ALCL) | ||
Expression in Non-Neoplastic Entities[]
Pertinent Negatives[]
This antigen is typically NOT expressed by the following entities:
Practical Uses / Panels[]
- ALK-1 positivity in Anaplastic Large Cell Lymphoma (ALCL) has a favorable prognostic significance (80% 5 year survival vs 40% 5 year survival observed in ALK-1 negative ALCLs).