Synonyms[]
- BCL6
- B cell lymphoma 6
Antibodies[]
Technical Info[]
Staining Pattern[]
- Nuclear
Expression in Normal Tissues[]
- Germinal center B-cells
Expression in Neoplastic Entities[]
Benign[]
| Tumor name | % Positive Staining | Number of Cases |
Intermediate/Uncertain Malignant Potential[]
| Tumor name | % Positive Staining | Number of Cases |
Malignant[]
| Tumor name | % Positive Staining | Number of Cases |
| *Germinal center type of diffuse large B-cell lymphoma (DLBCL)[1] | ||
- NOTE: DLBCL that is BCL-6+ can only be considered germinal center type in the context of NEGATIVE MUM1 (IRF4) staining. In other words, BCL-6+/MUM1+ DLBCL is considered to be "activated (non-germinal center) type". [1]
Expression in Non-Neoplastic Entities[]
Pertinent Negatives[]
This antigen is typically NOT expressed by the following entities: